Royal Peptides products are offered exclusively for laboratory research, analytical, and scientific applications. Not for human or veterinary use.
01Research Product Information
Royal Peptides supplies compounds intended for controlled laboratory research and analytical applications.
- For research and analytical use only
- Not intended for human consumption or administration
- Not intended for veterinary use
- Not represented as a drug, medicine, or therapeutic product
- Laboratory researchers are responsible for appropriate protocols and controls
02Lyophilized Product Format
Where applicable, Royal Peptides research materials are supplied in lyophilized form.
Lyophilization is a freeze-drying process used to remove moisture from material under controlled conditions.
- Material appearance may differ between compounds and production lots
- Lyophilized material may appear as a cake, film, or fragmented material
- The quantity of visible material may appear small relative to vial size
- Visual appearance alone does not establish identity or purity
03Storage & Laboratory Handling
Storage requirements may vary by compound, formulation, and production lot. Refer to the product label and available product-specific documentation.
- Protect research materials from excessive heat
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04Packaging & Quality Documentation
Packaging components may vary slightly between production lots. This can include vial closures, cap styles, label positioning, and external packaging.
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SLU-PP-332
SLU-PP-332 – SLU-PP-332 Research Compound
Order SLU-PP-332 directly from Royal Peptides: Pan-ERR Agonist Capsules, lot-tested before release. SLU-PP-332 activates estrogen-related receptors, the pathway behind its reputation as an “exercise mimetic” in mouse studies. Curious how it compares with the newer analogue? Read slu-pp-332 versus SLU-PP-915, or look at bam15, another metabolic research compound.
SLU-PP-332 is an experimental synthetic small-molecule pan-estrogen-related receptor agonist studied for activity across ERRα, ERRβ and ERRγ and for its role in preclinical research involving mitochondrial biology, oxidative metabolism, skeletal-muscle signaling and exercise-associated pathways.
Not for human or veterinary use, administration, ingestion, injection, compounding, diagnostic, therapeutic, clinical, or personal use.
Buy SLU-PP-332 Online
Pick your strength with the selector at the top of this page and add SLU-PP-332 to your cart. Prices are per unit or per kit as shown, and every order ships with lot documentation.
Need larger quantities of SLU-PP-332? Kits and wholesale boxes lower the unit price; see our wholesale research peptides options.
What Is SLU-PP-332?
SLU-PP-332 is a synthetic research compound developed as a pharmacological agonist of the estrogen-related receptor family of nuclear receptors.
Published experimental work characterizes SLU-PP-332 as active across ERRα, ERRβ and ERRγ, with greater potency toward ERRα reported in its original characterization.
Despite sometimes being grouped with peptide research products, SLU-PP-332 is not a peptide. It is a synthetic small molecule used experimentally to investigate pharmacological activation of estrogen-related receptor signaling.
How Does SLU-PP-332 Work in Research Models?
Estrogen-related receptors are transcriptional regulators associated with cellular energy metabolism. Experimental activation of these receptors provides researchers with a method for investigating ERR-dependent metabolic and mitochondrial pathways.
ERR signaling has been associated with biological processes including oxidative phosphorylation, fatty-acid metabolism, mitochondrial function and energy utilization in metabolically active tissues.
SLU-PP-332 Research Areas
Published preclinical research has made SLU-PP-332 a useful experimental tool across several areas of metabolic and mitochondrial biology.
Investigation of pharmacological activation across the ERRα, ERRβ and ERRγ nuclear-receptor family.
Research involving mitochondrial function, cellular respiration and pathways associated with oxidative energy metabolism.
Experimental investigation of oxidative skeletal-muscle characteristics and exercise-associated transcriptional responses.
Research involving fatty-acid oxidation, cellular energy utilization and ERR-regulated metabolic pathways.
SLU-PP-332 and PGC-1α
SLU-PP-332 is sometimes described online as a “PGC-1α activator.” That description can obscure its experimentally characterized primary pharmacology.
SLU-PP-332 is more precisely described as a synthetic pan-ERR agonist. PGC-1 family coactivators participate in broader transcriptional networks relevant to ERR signaling and mitochondrial energy metabolism.
Research classification: ERRα, ERRβ and ERRγ are the pharmacological receptor targets used to characterize SLU-PP-332. PGC-1α is relevant to the surrounding transcriptional biology rather than being presented as the compound’s direct primary target.
SLU-PP-332 and Mitochondrial Research
The connection between estrogen-related receptors and cellular energy regulation is one reason SLU-PP-332 has attracted substantial research interest.
ERR-regulated transcription participates in pathways associated with mitochondrial function, oxidative phosphorylation, fatty-acid oxidation and cellular energy metabolism.
Synthetic ERR agonists therefore provide experimental tools for studying how pharmacological activation of these transcriptional networks affects metabolic and mitochondrial biology in preclinical models.
Why Is SLU-PP-332 Studied as an Exercise Mimetic?
SLU-PP-332 has received considerable research attention because preclinical studies have examined whether pharmacological ERR activation can reproduce selected molecular and metabolic responses associated with aerobic exercise.
This has led to SLU-PP-332 being discussed within the experimental “exercise mimetic” field.
Important distinction: “Exercise mimetic” is a research concept. It does not establish that SLU-PP-332 reproduces the broad cardiovascular, neurological, musculoskeletal and metabolic effects of physical exercise in humans.
Is SLU-PP-332 Orally Bioavailable?
Later published research identified lack of oral bioavailability as an important pharmacokinetic limitation of SLU-PP-332.
That limitation contributed to medicinal-chemistry research into chemically distinct pan-ERR agonists with different pharmacokinetic properties, including SLU-PP-915.
SLU-PP-915 subsequently demonstrated biological activity following oral administration in mouse research, creating an important experimental distinction between the two compounds.
Compare ERR pharmacology, chemistry, oral activity, mitochondrial research and published preclinical evidence.
SLU-PP-332 Metabolism Research
Analytical research published in 2026 further characterized the in-vitro metabolism of SLU-PP-332 using liver-derived experimental systems and high-resolution mass-spectrometry techniques.
The investigators reported nine SLU-PP-332 metabolites in the experimental systems studied, including six Phase-I metabolites and three Phase-II conjugates.
These findings contribute to analytical characterization and metabolite identification. In-vitro metabolism studies should not be interpreted as establishing human pharmacokinetics or clinical safety.
SLU-PP-332 Research FAQ
What is SLU-PP-332?
SLU-PP-332 is an experimental synthetic small molecule studied as an agonist of ERRα, ERRβ and ERRγ.
Is SLU-PP-332 a peptide?
No. SLU-PP-332 is a synthetic small molecule rather than a peptide chain.
What receptors does SLU-PP-332 target?
Published experimental research characterizes SLU-PP-332 as a pan-estrogen-related receptor agonist with activity across ERRα, ERRβ and ERRγ.
Is SLU-PP-332 a PGC-1α activator?
Its more precise pharmacological classification is a pan-ERR agonist. PGC-1 family coactivators are relevant to the broader transcriptional networks surrounding ERR signaling.
Why is SLU-PP-332 called an exercise mimetic?
Preclinical research has examined whether pharmacological ERR activation can reproduce selected molecular responses associated with aerobic exercise. The term describes a research concept and does not establish substitution for exercise in humans.
Is SLU-PP-332 orally bioavailable?
Published research has identified lack of oral bioavailability as a limitation of SLU-PP-332.
Has SLU-PP-332 demonstrated human clinical efficacy?
The research discussed here is preclinical. Laboratory and animal findings do not establish human clinical efficacy, dosing or safety.
Published SLU-PP-332 Research
- Billon C, et al. (2023). Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chemical Biology. PubMed →
- Hampton CS, et al. (2023). Medicinal-chemistry research involving potent pan-ERR agonists and the subsequent development of SLU-PP-915. PubMed Central →
- Billon C, et al. (2026). An orally active estrogen receptor-related receptor agonist, SLU-PP-915, enhances aerobic exercise capacity. PubMed →
- Möller GM, et al. (2026). In Vitro Metabolism and Analytical Characterization of SLU-PP-332 and SLU-PP-915: Novel Pan-ERR Agonists With Doping Potential. Rapid Communications in Mass Spectrometry. PubMed →
Research Use Only: SLU-PP-332 is an experimental research compound. This material and the information presented here are intended for laboratory research and scientific-reference purposes only. Published laboratory and animal findings do not establish human dosing, efficacy or safety. Not for human consumption.
SLU-PP-332 Lot Testing & COA
Every SLU-PP-332 lot is independently tested before release; results are listed with our coas peptides. For background reading, see published SLU-PP-332 research on PubMed.
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Compounds often studied alongside SLU-PP-332:
Buying SLU-PP-332
Where can I buy SLU-PP-332?
Order SLU-PP-332 directly from Royal Peptides. Choose a format in the Buy section, check out securely and your order ships from U.S. stock with lot documentation.
How fast do orders ship?
Orders are dispatched from U.S. inventory, usually within one business day, with tracking.
SLU-PP-332 for Laboratory Research
SLU-PP-332 is supplied for laboratory research use only. Not for human or veterinary use.
Specifications
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COA / Testing
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