Royal Peptides products are offered exclusively for laboratory research, analytical, and scientific applications. Not for human or veterinary use.
01Research Product Information
Royal Peptides supplies compounds intended for controlled laboratory research and analytical applications.
- For research and analytical use only
- Not intended for human consumption or administration
- Not intended for veterinary use
- Not represented as a drug, medicine, or therapeutic product
- Laboratory researchers are responsible for appropriate protocols and controls
02Lyophilized Product Format
Where applicable, Royal Peptides research materials are supplied in lyophilized form.
Lyophilization is a freeze-drying process used to remove moisture from material under controlled conditions.
- Material appearance may differ between compounds and production lots
- Lyophilized material may appear as a cake, film, or fragmented material
- The quantity of visible material may appear small relative to vial size
- Visual appearance alone does not establish identity or purity
03Storage & Laboratory Handling
Storage requirements may vary by compound, formulation, and production lot. Refer to the product label and available product-specific documentation.
- Protect research materials from excessive heat
- Limit unnecessary exposure to direct light and moisture
- Keep containers securely closed when stored
- Follow product-specific temperature requirements when provided
- Use appropriate laboratory contamination-control procedures
04Packaging & Quality Documentation
Packaging components may vary slightly between production lots. This can include vial closures, cap styles, label positioning, and external packaging.
- Check the product label and lot identifier before laboratory use
- Inspect the vial and closure for visible shipping damage
- Packaging design may differ between batches
- Lot-specific analytical documentation may be available in our COA library
IGF-1 LR3 1mg
IGF-1 LR3 1mg – IGF-1 LR3 1mg — Long R3 IGF-1 Research Peptide
IGF-1 LR3 1mg ships from U.S. stock at Royal Peptides – Long-Acting IGF-1 Analogue, with a lot-matched COA. The LR3 modification (an arginine substitution plus a 13-amino-acid extension) lets IGF-1 avoid its binding proteins, extending activity in cell-culture models. Dosing math for 1mg vials is easiest with the peptide dilution calculator.
IGF-1 LR3 1mg, also known as Long R3 IGF-1, is a modified analog of insulin-like growth factor 1 developed for experimental research involving IGF-1 receptor signaling, cellular growth pathways, metabolism and growth-factor biology. Its modified structure distinguishes it from endogenous IGF-1 and makes it a widely recognized compound in laboratory growth-factor research.
Research Use Only
Not for human or veterinary use, administration, ingestion, injection, compounding, diagnostic, therapeutic, clinical, or personal use.

Order Online
Buy IGF-1 LR3 1mg Online
Pick your strength with the selector at the top of this page and add IGF-1 LR3 1mg to your cart. Prices are per vial or per kit as shown, and every order ships with lot documentation.
Buying more than one vial? Volume pricing applies automatically in the cart: 5% off at 3 vials and 10% off at 6 or more.
01
IGF-1 LR3 1mg — Long R3 IGF-1 Research Peptide
02
What Is IGF-1 LR3?
IGF-1 LR3 is a modified analog of insulin-like growth factor 1 (IGF-1), an endogenous signaling molecule involved in growth-factor biology.
The abbreviation LR3 refers to Long R3. The molecule differs structurally from native IGF-1 through an amino-acid substitution at position 3 together with an additional N-terminal peptide extension.
These structural modifications alter the molecule’s interaction with IGF-binding proteins while retaining its relevance to IGF-1 receptor (IGF1R) signaling research.
This makes IGF-1 LR3 useful in experimental systems designed to investigate growth-factor receptor activation, intracellular signaling and cellular responses under controlled laboratory conditions.
03
IGF-1 Receptor Signaling Research
A major area of IGF-1 LR3 research centers on the IGF-1 receptor (IGF1R).
IGF1R is a receptor tyrosine kinase. Ligand binding can initiate intracellular signaling networks that researchers investigate in relation to cellular growth, survival, differentiation and metabolism.
Two frequently investigated downstream signaling systems are the PI3K/AKT and MAPK/ERK pathways. These pathways participate in broad cellular signaling networks and are studied across many experimental models.
IGF1R Investigation of IGF-1 receptor binding and activation. PI3K / AKT Research involving intracellular metabolic and cellular signaling pathways. MAPK / ERK Investigation of signaling associated with cellular responses to growth factors.
04
Cellular Growth & Differentiation Research
Growth factors are important experimental tools for investigating how extracellular signals influence cellular behavior.
IGF-associated signaling has therefore been studied in laboratory models examining cell proliferation, differentiation, protein synthesis, survival signaling and cellular metabolism.
IGF-1 LR3 provides researchers with a modified IGF analog for investigating these pathways while separately characterizing the effects of its altered molecular structure.
05
Metabolic Signaling Research
The IGF signaling network intersects with several pathways involved in cellular nutrient sensing and metabolic regulation.
Experimental research can therefore use IGF-1 LR3 to examine relationships among growth-factor signaling, glucose metabolism, amino-acid signaling, protein synthesis and cellular energy pathways.
These are mechanistic research areas and should not be interpreted as evidence of a therapeutic effect from IGF-1 LR3.
06
IGF-1 LR3 Research Areas
Growth-Factor Biology Investigation of signaling initiated by growth-factor receptor systems. IGF1R Signaling Experimental characterization of IGF-1 receptor activity. Cellular Proliferation Laboratory investigation of growth-associated cellular signaling. Cell Differentiation Research into signaling associated with changes in cellular state and phenotype. Protein Synthesis Investigation of signaling pathways involved in cellular protein regulation. Metabolic Biology Study of interactions between growth-factor and metabolic signaling networks.
07
IGF-1 LR3 1mg Research Specifications
08
Why Is Long R3 IGF-1 Studied?
Long R3 IGF-1 is scientifically interesting because it combines recognizable IGF-1 receptor activity with structural modifications that distinguish it from endogenous IGF-1.
Researchers can therefore use the molecule to investigate both IGF receptor signaling and how structural changes to a growth-factor analog influence its biochemical interactions.
This has made IGF-1 LR3 a recurring experimental compound in studies involving growth-factor biology, receptor signaling and cellular metabolism.
09
IGF-1 LR3 1mg FAQ
What is IGF-1 LR3?
IGF-1 LR3, or Long R3 IGF-1, is a structurally modified analog of insulin-like growth factor 1 used in laboratory research involving IGF receptor signaling and growth-factor biology.
What does LR3 mean in IGF-1 LR3?
LR3 refers to Long R3. The analog contains an arginine substitution at position three along with an N-terminal peptide extension relative to native IGF-1.
Is IGF-1 LR3 the same as native IGF-1?
No. IGF-1 LR3 is a modified analog of IGF-1 and has structural differences that alter aspects of its biochemical behavior, including interactions with IGF-binding proteins.
What receptor is associated with IGF-1 LR3 research?
A primary research target is the insulin-like growth factor 1 receptor, commonly abbreviated IGF1R.
What pathways are investigated in IGF-1 research?
IGF-associated research frequently examines downstream signaling systems including PI3K/AKT and MAPK/ERK, along with broader cellular growth and metabolic signaling networks.
What is the strength of this IGF-1 LR3 product?
This research product contains 1mg of IGF-1 LR3 per vial.
Is IGF-1 LR3 1mg intended for human use?
No. This material is supplied strictly for laboratory and research purposes and is not intended for human or veterinary use.
Quality Documentation
IGF-1 LR3 1mg Lot Testing & COA
Every IGF-1 LR3 1mg lot is independently tested before release; results are listed with our third party tested peptides. For background reading, see published IGF-1 LR3 research on PubMed.
Related Research
Researchers Also Order
Compounds often studied alongside IGF-1 LR3:



Buying Questions
Buying IGF-1 LR3 1mg
Where can I buy IGF-1 LR3 1mg?
Order IGF-1 LR3 1mg directly from Royal Peptides. Choose a format in the Buy section, check out securely and your order ships from U.S. stock with lot documentation.
How fast do orders ship?
Orders are dispatched from U.S. inventory, usually within one business day, with tracking.
IGF-1 LR3 for Laboratory Research
IGF-1 LR3 1mg is supplied for laboratory research use only. Not for human or veterinary use.
Specifications
Product information pulled directly from WooCommerce.
COA / Testing
Review available analytical documentation for the applicable product and batch in the COA library.
View COA LibraryShipping & Storage
Shipping options and delivery estimates are shown at checkout. Refer to the product label for storage requirements.
Related Research Materials.




