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IGF-1 LR3 1mg

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For laboratory and research purposes only.Not intended for human consumption, diagnostic use, therapeutic use, or administration to humans or animals.
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Growth-Factor Signaling Research

IGF-1 LR3 1mg – IGF-1 LR3 1mg — Long R3 IGF-1 Research Peptide

IGF-1 LR3 1mg ships from U.S. stock at Royal Peptides – Long-Acting IGF-1 Analogue, with a lot-matched COA. The LR3 modification (an arginine substitution plus a 13-amino-acid extension) lets IGF-1 avoid its binding proteins, extending activity in cell-culture models. Dosing math for 1mg vials is easiest with the peptide dilution calculator.

IGF-1 LR3 1mg, also known as Long R3 IGF-1, is a modified analog of insulin-like growth factor 1 developed for experimental research involving IGF-1 receptor signaling, cellular growth pathways, metabolism and growth-factor biology. Its modified structure distinguishes it from endogenous IGF-1 and makes it a widely recognized compound in laboratory growth-factor research.

IGF-1 LR3Long R3 IGF-11mgIGF1R ResearchResearch Use Only

Research Use Only

Not for human or veterinary use, administration, ingestion, injection, compounding, diagnostic, therapeutic, clinical, or personal use.

IGF-1 LR3 1mg

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Single Vial$78
10 Vial Kit$590≈ $59 per vial

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01

IGF-1 LR3 1mg — Long R3 IGF-1 Research Peptide

CompoundIGF-1 LR3Content1mgCommon NameLong R3 IGF-1Research TargetIGF-1 Receptor

02

What Is IGF-1 LR3?

IGF-1 LR3 is a modified analog of insulin-like growth factor 1 (IGF-1), an endogenous signaling molecule involved in growth-factor biology.

The abbreviation LR3 refers to Long R3. The molecule differs structurally from native IGF-1 through an amino-acid substitution at position 3 together with an additional N-terminal peptide extension.

These structural modifications alter the molecule’s interaction with IGF-binding proteins while retaining its relevance to IGF-1 receptor (IGF1R) signaling research.

This makes IGF-1 LR3 useful in experimental systems designed to investigate growth-factor receptor activation, intracellular signaling and cellular responses under controlled laboratory conditions.

03

IGF-1 Receptor Signaling Research

A major area of IGF-1 LR3 research centers on the IGF-1 receptor (IGF1R).

IGF1R is a receptor tyrosine kinase. Ligand binding can initiate intracellular signaling networks that researchers investigate in relation to cellular growth, survival, differentiation and metabolism.

Two frequently investigated downstream signaling systems are the PI3K/AKT and MAPK/ERK pathways. These pathways participate in broad cellular signaling networks and are studied across many experimental models.

IGF1R Investigation of IGF-1 receptor binding and activation. PI3K / AKT Research involving intracellular metabolic and cellular signaling pathways. MAPK / ERK Investigation of signaling associated with cellular responses to growth factors.

04

Cellular Growth & Differentiation Research

Growth factors are important experimental tools for investigating how extracellular signals influence cellular behavior.

IGF-associated signaling has therefore been studied in laboratory models examining cell proliferation, differentiation, protein synthesis, survival signaling and cellular metabolism.

IGF-1 LR3 provides researchers with a modified IGF analog for investigating these pathways while separately characterizing the effects of its altered molecular structure.

05

Metabolic Signaling Research

The IGF signaling network intersects with several pathways involved in cellular nutrient sensing and metabolic regulation.

Experimental research can therefore use IGF-1 LR3 to examine relationships among growth-factor signaling, glucose metabolism, amino-acid signaling, protein synthesis and cellular energy pathways.

These are mechanistic research areas and should not be interpreted as evidence of a therapeutic effect from IGF-1 LR3.

06

IGF-1 LR3 Research Areas

Growth-Factor Biology Investigation of signaling initiated by growth-factor receptor systems. IGF1R Signaling Experimental characterization of IGF-1 receptor activity. Cellular Proliferation Laboratory investigation of growth-associated cellular signaling. Cell Differentiation Research into signaling associated with changes in cellular state and phenotype. Protein Synthesis Investigation of signaling pathways involved in cellular protein regulation. Metabolic Biology Study of interactions between growth-factor and metabolic signaling networks.

07

IGF-1 LR3 1mg Research Specifications

CompoundIGF-1 LR3
Content1mg
Alternative NameLong R3 IGF-1
Compound TypeModified IGF-1 Analog
Primary Research TargetIGF-1 Receptor (IGF1R)
Research CategoryGrowth-Factor Signaling

08

Why Is Long R3 IGF-1 Studied?

Long R3 IGF-1 is scientifically interesting because it combines recognizable IGF-1 receptor activity with structural modifications that distinguish it from endogenous IGF-1.

Researchers can therefore use the molecule to investigate both IGF receptor signaling and how structural changes to a growth-factor analog influence its biochemical interactions.

This has made IGF-1 LR3 a recurring experimental compound in studies involving growth-factor biology, receptor signaling and cellular metabolism.

09

IGF-1 LR3 1mg FAQ

What is IGF-1 LR3?

IGF-1 LR3, or Long R3 IGF-1, is a structurally modified analog of insulin-like growth factor 1 used in laboratory research involving IGF receptor signaling and growth-factor biology.

What does LR3 mean in IGF-1 LR3?

LR3 refers to Long R3. The analog contains an arginine substitution at position three along with an N-terminal peptide extension relative to native IGF-1.

Is IGF-1 LR3 the same as native IGF-1?

No. IGF-1 LR3 is a modified analog of IGF-1 and has structural differences that alter aspects of its biochemical behavior, including interactions with IGF-binding proteins.

What receptor is associated with IGF-1 LR3 research?

A primary research target is the insulin-like growth factor 1 receptor, commonly abbreviated IGF1R.

What pathways are investigated in IGF-1 research?

IGF-associated research frequently examines downstream signaling systems including PI3K/AKT and MAPK/ERK, along with broader cellular growth and metabolic signaling networks.

What is the strength of this IGF-1 LR3 product?

This research product contains 1mg of IGF-1 LR3 per vial.

Is IGF-1 LR3 1mg intended for human use?

No. This material is supplied strictly for laboratory and research purposes and is not intended for human or veterinary use.

Quality Documentation

IGF-1 LR3 1mg Lot Testing & COA

Every IGF-1 LR3 1mg lot is independently tested before release; results are listed with our third party tested peptides. For background reading, see published IGF-1 LR3 research on PubMed.

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Buying Questions

Buying IGF-1 LR3 1mg

Where can I buy IGF-1 LR3 1mg?

Order IGF-1 LR3 1mg directly from Royal Peptides. Choose a format in the Buy section, check out securely and your order ships from U.S. stock with lot documentation.

How fast do orders ship?

Orders are dispatched from U.S. inventory, usually within one business day, with tracking.

Research Use Only

IGF-1 LR3 for Laboratory Research

IGF-1 LR3 1mg is supplied for laboratory research use only. Not for human or veterinary use.